New monograph: Nerlynx® [neratinib] for HER2-overexpressed/amplified breast cancer (specialist use only).
New monograph: Vaborem® [meropenem with vaborbactam] for complicated urinary-tract infection [including pyelonephritis], complicated intra-abdominal infection, hospital-acquired pneumonia, ventilator-associated pneumonia, bacteraemia [occurring in association with or suspected to be associated with the licensed indications], and aerobic Gram-negative infections [in patients with limited treatment options] (administered on expert advice).
New monograph: Xospata® [gilteritinib] for FLT3 mutation-positive acute myeloid leukaemia (specialist use only).
New preparations: Pepto-Bismol® [bismuth subsalicylate] for Helicobacter pylori eradication [in combination with other drugs (see Helicobacter pylori infection)].
New preparations: Softacort® [hydrocortisone eye drops] for local treatment of conjunctival inflammation (short-term).
Ambrisentan (Volibris®): patient alert card available [MHRA/CHM advice].
Carfilzomib (Kyprolis®): risk of reactivation of hepatitis B virus [MHRA/CHM advice].
Chronic obstructive pulmonary disease: updated guidance on management.
Dyspepsia, Gastro-oesophageal reflux disease, and Peptic ulcer disease: updated guidance and dosing regimens.
Fluocinolone acetonide intravitreal implant for treating chronic diabetic macular oedema in phakic eyes after an inadequate response to previous therapy [NICE guidance].
Helicobacter pylori infection: updated guidance and dosing regimens.
Neratinib for extended adjuvant treatment of hormone receptor-positive, HER2-positive early stage breast cancer after adjuvant trastuzumab [NICE guidance].
Pentosan polysulfate sodium for treating bladder pain syndrome [NICE guidance].
Rucaparib for maintenance treatment of relapsed platinum-sensitive ovarian, fallopian tube or peritoneal cancer [NICE guidance].