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March 2017 Share this issue Facebook LinkedIn Twitter
I Welcome
Welcome to the March BNF eNewsletter.
BNF 73 - available this month!
This month sees the publication of the new BNF 73. Read on for more details and pre-order your copies now!

Ten new drug monographs have been added to the BNF in the last month, including - Cobimetinib, Carfilzomib, Evolocumab, Talimogene, Trametinib and Osimertinib.

This issue includes MHRA advice on increased risk of interaction with vitamin K antagonists and direct-acting antivirals, and the use of acetylcysteine for paracetamol overdose. You will also find NICE technology appraisals for Evolocumab, Mepolizumab, Trametinib, Everolimus, Imatinib and Ticagrelor.

Kind regards,
BNF Team
I In this issue
BNF 73 available More >  
Significant changes More >  
How to purchase BNF More >  
Price reminder More >  
Drug safety update More >  
Feedback More >  
BNF BNF 73 available to order now
BNF 73 has been revised and updated to reflect best practice as well as up-to-date legal and professional guidelines relating to the uses of medicines. Access to the latest edition is vital for healthcare professionals, giving reliable guidance on prescribing, dispensing, and administering medicines. In addition, NICE have formally accredited the editorial process used by the British National Formulary to produce its resources.

New content updates include:
Updated guidance for conditions including anal fissure, coeliac disease, dementia, exocrine pancreatic insufficiency, food allergy, multiple sclerosis and short bowel syndrome. New prescribing guidance for biological and biosimilar medicines
New drug monographs alirocumab, blinatumomab, brivaracetam, ceftobiprole, clevidipine, elvitegravir, isavuconazole, nivolumab and panobinostat
New safety information about fire risk with paraffin-based skin emollients on dressings and clothing and advice on minimising the risk of infections when being treated with idelalisib
Updated guidance on starting routine for oral progestogen-only contraceptives and the use of sodium glucose co-transporter 2 inhibitors as monotherapy for treating type 2 diabetes
Find out more and order BNF 73 here.
BNF 71

ISBN: 978 0 85711 276 7
March 2017 • Paperback • 1,536pp

I Significant
This month's changes to the clinical content of these publications are described in two parts:

BNF and BNFC update should be read by all users
BNF update should be read by all users of the BNF
BNF 72 - BNFC 2016-2017
BNF Update
Cobimetinib: new drug monograph
For further information, see cobimetinib.
Mepolizumab: new drug monograph
For further information, see mepolizumab.
Trametinib: risk of gastrointestinal perforation and colitis (MHRA advice)
For further information, see trametinib.
Osimertinib: new drug monograph
For further information, see osimertinib.
NICE technology appraisal update:
NICE technology appraisals that have been added to the BNF this month include:
Everolimus with exemestane for treating advanced breast cancer after endocrine therapy
Pertuzumab for the neoadjuvant treatment of HER2-positive breast cancer
Ticagrelor for preventing atherothrombotic events after myocardial infarction
Other changes
To review other changes in the BNF, click on changes.
BNF BNF for Children Update
Dose changes
Nystatin for oral candidiasis.
For further information, see nystatin.
The changes have been added to the news page.
Acetylcysteine: intravenous acetylcysteine for paracetamol overdose: reminder of authorised dose regimen; possible need for continued treatment (MHRA advice)
For further information, see acetylcysteine.
Evolocumab: new drug monograph
For further information, see evolocumab.
I How to purchase BNF
Purchase Print copies
Purchase print copies
To order the March 2017 edition, visit the Pharmaceutical Press website.
Purchase a print subscription
Purchase a print subscription and save money
A print subscription is the best way to ensure access to the latest copy of BNF as soon as it publishes.
BNF online
BNF online
Outside the UK, content is available via a subscription to MedicinesComplete.
Email us
BNF eBook
BNF eBook
BNF is also available as a PDF eBook.
I Monthly price update reminder
Prices of all branded medicinal products in the BNF and BNFC are now updated monthly. Prices of generic preparations of medicinal products are updated every 2-4 months, to coincide with print editions of BNF and BNF for Children. The BNF team keeps price information up to date using data sourced from the NHS dictionary of medicines and devices (dm+d).
Drug Safety Update
Drug Safety Update is a monthly newsletter from
the MHRA and Commission on Human Medicine.
Please follow this link to review this month's Drug Safety Update.
I Feedback on our eNewsletter
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