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November 2018 Share this issue Facebook LinkedIn Twitter
 
I Welcome
Welcome to the November BNF eNewsletter.
Three new drug monographs have been added to the BNF in the last month, doxylamine with pyridoxine, ospemifene, and streptozocin.

We have also included dose changes for levonorgestrel intrauterine devices and tolvaptan (Jinarc® and Samsca®), and have updated guidance on the management of dementia. We have included MHRA advice on transdermal fentanyl patches and the risk of life-threatening and fatal opioid toxicity from accidental exposure, particularly in children, and ponatinib (Iclusig®) and reports of posterior reversible encephalopathy syndrome. You will also find NICE technology appraisals for inotuzumab ozogamicin for treating relapsed or refractory B-cell acute lymphoblastic leukaemia, and pembrolizumab for treating relapsed or refractory classical Hodgkin lymphoma.
Kind regards,
BNF Team
I In this issue
BNF customer survey More >  
BNF app wins silver More >  
Significant changes More >  
BNF 76 & BNFC 2018-2019 available More >  
News More >  
How to purchase BNF More >  
Drug safety update More >  
Feedback More >  
I The BNF customer survey - share your views with us!
How often do you use the BNF? Does BNF content give you more confidence in your healthcare role or in your research? Here's your chance to tell us why and how you use the BNF in our customer survey.

Click here to tell us more about how you use the BNF

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BNF
I BNF app wins silver in 2018 London Design Awards
The British National Formulary (BNF) App has won Silver in the London Design Awards 2018. Following on from recent recognition by the BIMA awards for 'best website & app' this latest win illustrates the impact that thoughtful design and functionality of the app is having on the user experience of healthcare professionals.

The BNF App continues to be a success, providing comprehensive information about all the prescription medicines available on the NHS. Each month over 126,000 clinicians use the App to prescribe and advise on the use of medicines. Its core feature is an interaction checker that helps clinicians ensure the safety of their patients by intuitively checking for possible drug interactions.

Learn more about the BNF app.
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I Significant changes
This month's changes to the clinical content of these publications are described in two parts:

BNF and BNFC update should be read by all users
BNF update should be read by all users of the BNF
BNF 76 - BNFC 2018-2019
BNF BNF for Children Update
Transdermal fentanyl patches: life-threatening and fatal opioid toxicity from accidental exposure, particularly in children [MHRA advice]
For further information, see fentanyl.
Dose changes
Levonorgestrel [update to timings of administration of intra-uterine devices and advice on additional contraceptive precautions]
For further information, see levonorgestrel.
BNF Update
Doxylamine with pyridoxine: new drug monograph
For further information, see doxylamine with pyridoxine.
Ospemifene: new drug monograph
For further information, see ospemifene.
Streptozocin: new drug monograph
For further information, see streptozocin.
Dementia: updated guidance on management
For further information, see dementia.
Dose changes
Tolvaptan (Jinarc®) [update to indication and addition of dosing recommendations for use with potent and moderate CYP3A4 inhibitors]
For further information, see tolvaptan.
Tolvaptan (Samsca®) [option of reduced starting dose for patients at risk of overly rapid correction of serum-sodium concentration]
For further information, see tolvaptan.
NICE technology appraisal update:
NICE technology appraisals that have been added to the BNF this month include:
Pembrolizumab for treating relapsed or refractory classical Hodgkin lymphoma
Inotuzumab ozogamicin for treating relapsed or refractory B-cell acute lymphoblastic leukaemia
Other changes
To review other changes in the BNF, click on changes.
I BNF 76 and BNFC 2018-2019 available now!
Each year NICE provides print copies of the BNF and BNFC to prescribers working in the NHS and other organisations that provide NHS-commissioned care in England. Print versions of BNF 76 and BNFC 2018-2019 are to be distributed throughout October and November. If you have any queries regarding eligibility/print distribution lists please contact BNF@wilmingtonhealthcare.com.

As content is continually updated to reflect the latest evidence from credible sources worldwide, now is the time to hand back your old editions and collect a new version. You can also access up-to-date guidance on prescribing, dispensing, and administering medicines via BNF/BNFC on Medicines Complete, the NICE website and the award winning BNF&BNFC app.
BNF 76 - BNFC 2018-2019
Please donate old copies of the BNF!
Old BNF copies can be donated to certain Commonwealth countries via the Pharmaid scheme of the Commonwealth Pharmacists Association. For more information on this scheme click here. If you would like to donate your copy email: admin@commonwealthpharmacy.org.
I News
Reminder - help from CPPE with BNF 76
An interactive PDF e-learning programme from the Centre for Pharmacy Postgraduate Education (CPPE) will help you familiarise yourself with recommendations in BNF 76. It comprises 10 practical case studies that help you keep up to date with recent changes in the BNF, and can be accessed here.
BNF 74
I How to purchase BNF
Purchase Print copies
Purchase print copies
To order the March 2018 edition, visit the Pharmaceutical Press website.
More
Purchase a print subscription
Purchase a print subscription and save money
A print subscription is the best way to ensure access to the latest copy of BNF as soon as it publishes.
More
BNF online
BNF online
Outside the UK, content is available via a subscription to MedicinesComplete.
Email us
BNF eBook
BNF eBook
BNF is also available as a PDF eBook.
More
Drug Safety Update
Drug Safety Update is a monthly newsletter from
the MHRA and Commission on Human Medicine.
Please follow this link to review this month's Drug Safety Update.
I Feedback on our eNewsletter
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Medicines Complete BNF Pharmaceutical Press
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