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Martindale 39e

Drugs and the Liver

A guide to drug handling in liver dysfunction

First edition

Edited by Penny North-Lewis

Drugs and the Liver is designed to assist practitioners in making pragmatic choices for their patients.

Liver disease is a widespread and increasing problem throughout the world, however little is published on how different types and degrees of liver dysfunction affect the body's ability to handle medicines.

This book aims:
  • to enable the practitioner to assess liver function using biochemical markers, other tests, signs, symptoms and disease knowledge
  • to identify which pharmacokinetic and pharmacodynamic parameters of a drug are likely to be affected by different types of liver disease
  • to consider the impact of a drug's side effects on a patient with liver disease.
This practical guide covers background information on liver function, the principles of drug use in liver disease and includes a section of worked examples of commonly asked questions. It will be invaluable to clinical pharmacists and anyone making medicine choices in patients with liver impairment.
Drugs and the Liver




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