Clarke's Analysis of Drugs and Poisons
Moffat, Anthony C; Osselton, M David; Widdop, Brian; Watts, Jo
Edited by Anthony C Moffat - Emeritus Professor, Centre for Pharmaceutical Analysis, The School of Pharmacy, University of London, UK, M David Osselton - Head, Centre for Forensic Sciences, School of Conservation Studies, Bournemouth University, UK, Brian Widdop - Emeritus Doctor. Formerly, Laboratory Director, Medical Toxicology Unit, Guy's Hospital, London, UK, and Jo Watts - Executive Development Editor, Royal Pharmaceutical Society of Great Britain, London, UK
Clarke's Analysis of Drugs and Poisons is the definitive source of analytical data for drugs and poisons. Written by over 40 international experts, the resource also boasts an editorial advisory board of over 45 world renowned scientists.
This reference work has been completely revised and updated for the new edition, and comprises two volumes.
The book is essential for all forensic and clinical toxicologists, pathologists, hospital pharmacists, pharmaceutical analysts, clinical pharmacologists, clinical and forensic laboratories, and poison information centres.
Clarke's Analysis of Drugs and Poisons is also available as an eBook.
Part one: methodology and analytical techniques
Contains 44 chapters by leading international scientists covering the practice areas and analytical procedures used in toxicology
Parts two and three: analytical and toxicological data
Contains 2111 drug and poison monographs detailing physical properties, analytical methods, pharmacokinetic data and toxicity data.
Part four: Indexes to analytical data
This part contains indexes of analytical data, including all data for colour tests, chromatography, ultraviolet spectrophotometry, infrared spectrometry and mass spectrometry.
"This continues to be an invaluable reference for pharmaceutical scientists, clinical and forensic toxicologists and environmental chemists...Both the number of substances discussed in the monograph section and the depth of information presented are quite impressive."
Randall C. Baselt, Ph.D., Journal of Forensic Science, 2011
2011, TIAFT Bulletin
"Pathologists, clinicians, lawyers and students will find the new Clarke engaging, systematic in its approach and daunting in the massive amount of information provided. It is not until you become accustomed with the layout and logical style of the book that one appreciates the thought that has gone into producing this excellent and essential reference. No toxicologist should be without one!"
Dimitri Gerostamoulos, TIAFT Bulletin 41(2), 2011
"The work provides a compilation and easy access to analytical data for numerous compounds that can give an overview without the need of an extensive database search. This is especially true for data of older compounds that cannot be easily found elsewhere...the reader is provided with substantial information making the work an incomparable reference book in drug analysis."
Gerhard K.E. Scriba, Department of Pharmaceutical Chemistry, University of Jena, Chromatographia, 10 July 2011
From the reviews of the previous edition
'Some things in life are worth the wait and truly this 3rd edition of Clarke's Analysis of Drugs and Poisons falls into this category…the quality is superb' Australian Journal of Forensic Sciences
'Clarke has gained an international reputation as a reliable source of information for the analyses of drugs, and this new highly-expanded edition is the 21st century's successor.' Veterinary and Human Toxicology
'The content is comprehensive, absorbing and layout is well planned and executed. Without doubt, this volume will be a much well thumbed institution in any serious analytical laboratory and will assist generations of scientists in years to come.' Pharmacy Education
- Volume one has been greatly expanded from 31 to 44 chapters providing extensive coverage of all methodology and analytical techniques. Of significant interest include:
- Quality control and assessment - separated into two chapters to reflect the differing situations/purposes/remits of the toxicology laboratory versus the pharmaceutical industry (accreditation with ISO17025 becoming the international standard in labs)
- Method development and validation - now present since reliable analytical techniques and data should be of the utmost importance to any analyst
- 'Sampling, storage and stability', 'Measuring and reporting uncertainty' and 'Interpretation of results' now included to cover all aspects accreditation
- Pharmacokinetics now coupled with Pharmacogenomics
- All chapters have been updated, for instance the colour test chapter now includes the analysis of metals, while newer analytical techniques, such as liquid chromatography-mass spectrometry (LC-MS) and atomic absorption spectrometry-inductively coupled- mass spectrometry (AAS-ICP-MS) are also covered.
- Parts two and three now contain 2111 monographs (1730 in 3rd edition). This includes over 200 new monographs with retention of all monographs included in previous edition. New monographs include metals, natural toxins and weapons of mass destruction
- Over 300 updated monographs including amphetamine, morphine and MDMA
MedicinesComplete provides access to an extensive range of the world's most trusted drug information resources including Clarke's Analysis of Drugs and Poisons. Intuitive, flexible and cost-effective, this unique collection of evidence based, unbiased pharmaceutical information forms the definitive solution empowering informed, safe and fast decisions.
Clarke's Analysis of Drugs and Poisons will be updated annually on MedicinesComplete.
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ISBN 978 0 85369 711 4
Published May 2011
276 x 219mm (2736pp)
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