Clarke's Analysis of Drugs and Poisons is the definitive source of analytical data for drugs and poisons. Written by over 40 international experts, the resource also boasts an editorial advisory board of over 45 world renowned scientists.

This reference work has been completely revised and updated for the new edition, and comprises two volumes.

The book is essential for all forensic and clinical toxicologists, pathologists, hospital pharmacists, pharmaceutical analysts, clinical pharmacologists, clinical and forensic laboratories, and poison information centres.

Clarke's Analysis of Drugs and Poisons is also available as an eBook.

Volume one

Part one: methodology and analytical techniques

Contains 44 chapters by leading international scientists covering the practice areas and analytical procedures used in toxicology

Volumes two

Parts two and three: analytical and toxicological data

Contains 2111 drug and poison monographs detailing physical properties, analytical methods, pharmacokinetic data and toxicity data.

Part four: Indexes to analytical data

This part contains indexes of analytical data, including all data for colour tests, chromatography, ultraviolet spectrophotometry, infrared spectrometry and mass spectrometry.

Randall C. Baselt, Ph.D., Journal of Forensic Science, 2011

Dimitri Gerostamoulos, TIAFT Bulletin 41(2), 2011

10-Jul-2011, Chromatographia
"The work provides a compilation and easy access to analytical data for numerous compounds that can give an overview without the need of an extensive database search. This is especially true for data of older compounds that cannot be easily found elsewhere...the reader is provided with substantial information making the work an incomparable reference book in drug analysis."

Gerhard K.E. Scriba, Department of Pharmaceutical Chemistry, University of Jena, Chromatographia, 10 July 2011

From the reviews of the previous edition

'Some things in life are worth the wait and truly this 3rd edition of Clarke's Analysis of Drugs and Poisons falls into this category…the quality is superb' Australian Journal of Forensic Sciences

'Clarke has gained an international reputation as a reliable source of information for the analyses of drugs, and this new highly-expanded edition is the 21st century's successor.' Veterinary and Human Toxicology

'The content is comprehensive, absorbing and layout is well planned and executed. Without doubt, this volume will be a much well thumbed institution in any serious analytical laboratory and will assist generations of scientists in years to come.' Pharmacy Education

• Volume one has been greatly expanded from 31 to 44 chapters providing extensive coverage of all methodology and analytical techniques. Of significant interest include:

1. Quality control and assessment - separated into two chapters to reflect the differing situations/purposes/remits of the toxicology laboratory versus the pharmaceutical industry (accreditation with ISO17025 becoming the international standard in labs)
2. Method development and validation - now present since reliable analytical techniques and data should be of the utmost importance to any analyst
3. 'Sampling, storage and stability', 'Measuring and reporting uncertainty' and 'Interpretation of results' now included to cover all aspects accreditation
4. Pharmacokinetics now coupled with Pharmacogenomics

• All chapters have been updated, for instance the colour test chapter now includes the analysis of metals, while newer analytical techniques, such as liquid chromatography-mass spectrometry (LC-MS) and atomic absorption spectrometry-inductively coupled- mass spectrometry (AAS-ICP-MS) are also covered.
• Parts two and three now contain 2111 monographs (1730 in 3^rd edition). This includes over 200 new monographs with retention of all monographs included in previous edition. New monographs include metals, natural toxins and weapons of mass destruction
• Over 300 updated monographs including amphetamine, morphine and MDMA

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