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Basic Pharmacokinetics Second Edition

Basic Pharmacokinetics Second Edition

By Sunil S. Jambhekar and Philip J Breen

$85.00

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Textbook that provides an understanding of the principles of pharmacokinetics and biopharmaceutics.

ISBN9780853699804
Published1st Mar, 2012
TypePaperback
Dimensions246 x 189 mm
Page count496

Description

Basic Pharmacokinetics provides an understanding of the principles of pharmacokinetics and biopharmaceutics.   This book addresses clearly and concisely how these principles can be applied to achieve successful drug therapy. The applications of principles and equations are illustrated with related problem sets and problem solving exercises.   Features include:

  • the use of profiles (sketches of relationships among pharmacokinetic variables and parameters)
  • learning objectives
  • complete review of mathematical tools required to practice pharmacokinetics.

This edition has been revised and updated to include:

  • new chapters on metabolite pharmacokinetics and pharmacokinetic data fitting
  • expanded question data base to include multiple choice questions and true/false questions
  • a large increase in the number of questions based on pharmacokinetic profiles.

Basic Pharmacokinetics is an invaluable textbook for students.

Introduction and Overview

• Mathematical Review
• Intravenous Bolus Administration (One-compartment Model)
• Clearance Concepts

Problem Set 1

  • Drug Absorption From the Gastrointestinal Tract
  • Extravascular Routes of Drug Administration

Problem Set 2
• Bioavilability/bioequivalence

Problem Set 3
• Factors Affecting Drug Absorption: Physicochemical Factors
• Gastrointestinal Absorption: Role of the Dosage Form
Continuous Intravenous Infusion (One-compartment Model)

Problem Set 4
• Multiple Dosing: Intravenous Bolus Administration
• Multiple Dosing: Extravascular Routes of Drug Administration

Problem Set 5
• Two-compartment Model

Problem Set 6
• Multiple Intermittent Infusions

Problem Set 7
• Nonlinear Pharmacokinetics

Problem Set 8
• Drug Interactions

Problem Set 9
• Pharmacokinetic and Pharmacodynamic Relationships

Problem Set 10
• Metabolite Pharmacokinetics
• Pharmacokinetic Data Fitting
• Pharmacokinetics and Pharmacodynamics of Biotechnology Drugs

Appendix: Statistical Moment Theory in Pharmacokinetics

 

 

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