An Introduction to Clinical Pharmaceutics

An Introduction to Clinical Pharmaceutics
First edition
Alexander T Florence - Former Dean, School of Pharmacy, University of London, UK

This unique textbook considers the role of basic pharmaceutics in determining or modifying clinical outcomes and in explaining the behavior of medicines in the body, including adverse reactions due to formulations and excipients.

An Introduction to Clinical Pharmaceutics covers recent developments such as personalised therapies and nanotechnology.All of the principles underpinning clinical pharmaceutics are supported using relevant examples from recent literature and clinical case studies, including issues of:

formulation and excipients
surface tension
rheology
solubility
crystallisation and precipitation
aggregation
absorption

Examples and implications of each phenomenon are discussed with a reminder of the underlying pharmaceutics.

This book is aimed at undergraduate pharmacy students, those on taught Masters courses of clinical and hospital pharmacy, and new practitioners who require an updating on the relevance of the subject that is virtually unique to pharmacy.

Contents:
Introduction: Book Outline: 1. What Is Clinical Pharmaceutics?: 2. Excipients: Not Always Inert: 3. Thinking Chemically: 4. Looking at Formulations: 5. Adverse Events and Formulations and Devices: 6. Generic Medicines: Conventional Drugs and Biologicals: 7. Paediatric, Geriatric Medicines and Special Formulations: 8. The Future: Delivery Systems for Modern Therapeutics