Email not displaying correctly? View it in your browser
Forward to a colleague | Sign up to BNF eNews
BNF BNF for Children Medicines Complete
August 2016 Share this issue Facebook LinkedIn Twitter
I The latest updates in the BNF - find out more...
I Welcome
Welcome to the August BNF eNewsletter.
This month's issue includes notifications of the new drug monograph naloxegol and drug safety updates (DSUs) for canagliflozin, pomalidomide and tyrosine kinase inhibitors. We outline new guidance for Coeliac disease and updated guidance for irritable bowel syndrome in children. You'll also find NICE technology appraisals for canagliflozin, dapagliflozin, empagliflozin and naloxegol.

How are you finding our redesigned eNewsletter? Let us know in the Feedback section at the end of this eNews.
Kind regards,
BNF Team
I In this issue
Significant changes More >  
News More >  
How to purchase BNF More >  
Price reminder More >  
Drug safety update More >  
Feedback More >  
I Significant
This month's changes to the clinical content of these publications are described in three parts:

BNF & BNFC update should be read by all users of the BNF or BNF for Children
BNF update should be read by all users of the BNF
BNFC update should be read by all users of the BNF for Children
BNF 71
BNF BNF for Children Update
Miconazole and coumarins (e.g. warfarin): updated interaction advice
In line with a recent MHRA Drug Safety Update, the information in the BNF has been updated to clarify that miconazole (including oral gel and possibly vaginal and topical formulations) greatly enhances the anticoagulant effect of coumarins - concomitant use should be avoided if possible.

For further information on this interaction, see MHRA Drug Safety Update.
BCR-ABL tyrosine kinase inhibitors (bosutinib, imatinib, dasatinib, nilotinib and ponatinib): MHRA/CHM advice on risk of hepatitis B virus reactivation
For further information, see individual drugs.
Coeliac disease - new guidance on management
For further information, see Coeliac disease.
BNF for Children Update
Irritable bowel syndrome: updated guidance on management
For further information, see Irritable bowel syndrome.
Other changes
To review other changes in BNFC, click on changes.
BNF Update
Pomalidomide: MHRA/CHM advice on risk of hepatitis B reactivation
For further information, see Pomalidomide.
Canagliflozin: MHRA/CHM advice on risk of lower extremity amputations in patients with high cardiovascular risk
For further information, see Canagliflozin.
Naloxegol: new drug monograph
For further information, see Naloxegol.
NICE technology appraisals
NICE technology appraisals that have been added to the BNF this month include:
Canagliflozin, dapagliflozin and empagliflozin as monotherapies for treating type 2 diabetes
Naloxegol for treating opioid-induced constipation
For a list of all NICE technology appraisals added in this update, see changes.
I News
Coming soon! BNF 72 and BNFC 2016-2017
The latest versions of the BNF (BNF 72) and the BNF for Children 2016-2017 are in the final stages of preparation, and will shortly go to print. Fully updated with the latest developments, both will be available in September.
BNF 72 and BNFC 2016-2017
The changes to FormularyComplete (FC) are here - making your experience better and bringing your formulary in line with the new BNF structure. The new FC will have the same functionality as the existing version, but with many improvements - making data access faster and easier. Watch this space for more details, or contact
BNF 71
Reminder - help from the CPPE with BNF
CPPE have produced a guide to using the BNF, which you can access on their website here.
I How to purchase BNF
Purchase Print copies
Purchase print copies
To order the March 2016 edition, visit the Pharmaceutical Press website.
Purchase a print subscription
Purchase a print subscription and save money
A print subscription is the best way to ensure access to the latest copy of BNF as soon as it publishes.
BNF online
BNF online
Outside the UK, content is available via a subscription to MedicinesComplete.
Email us
BNF eBook
BNF eBook
BNF is also available as a PDF eBook.
We offer preferential pricing for bulk orders and for members of various professional associations. So if you are buying on behalf of a CCG, Health Board, NHS Trust or other organisation, contact us here. GPs should contact their CCG direct, who can obtain a discount when placing a centralised bulk order.
I Monthly price update reminder
Prices of all branded medicinal products in the BNF and BNFC are now updated monthly. Prices of generic preparations of medicinal products are updated every 2-4 months, to coincide with print editions of BNF and BNF for Children. The BNF team keep price information up to date using data sourced from the NHS dictionary of medicines and devices (dm+d).
Drug Safety Update
Drug Safety Update is a monthly newsletter from
the MHRA and Commission on Human Medicine.
Please follow this link to review this month's Drug Safety Update.
I Feedback on our eNewsletter
Please let us know if there are any issues that you'd like us to address in our eNewsletters, and if you have any comments on the new design. We welcome your feedback. If you have any comments or suggestions, please let us know at
Subscribe to this eNewsletter here
I Related Products
Medicines Complete BNF Pharmaceutical Press
Copyright © 2016 BMJ Publishing Group Ltd and the Royal Pharmaceutical Society of Great Britain. All rights reserved. Terms of use.
BNF for Children
Copyright © 2016 BMJ Publishing Group Ltd, the Royal Pharmaceutical Society of Great Britain and RCPCH Publications. All rights reserved. Terms of use.
If you do not wish to receive such mailings in the future please click here to unsubscribe.
Pharmaceutical Press, 66-68 East Smithfield, London, E1W 1AW, United Kingdom.