Clinical Pharmacokinetics

Clinical Pharmacokinetics is a practical guide to the use of pharmacokinetic principles in clinical practice. Over 30 clinical cases with self-study questions and answers are presented throughout to bridge the gap between pharmacokinetic concepts and their practical application to individual patients.

Pharmacokinetics is the study of the process of drug absorption, distribution, metabolism and elimination. The aim of applying pharmacokinetic principles is to individualise the dose of drug, and optimise the outcome achieved in each patient.

Its application reduces the chance of under-treatment, inadvertent poisoning and dose related adverse effects.

1. Basic pharmacokinetics

2. Therapeutic drug monitoring

3. Clinical pharmacokinetics in renal impairment

4. The effect of liver dysfunction on pharmacokinetics

5. Clinical pharmacokinetics in the elderly

6. Aminoglycosides

7. Digoxin

8. Theophylline

9. Lithium

10. Antiepileptics

11. Ciclosporin

12. Clinical case studies

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01-Dec-06, Irish Pharmacy Journal
'...the language in the book [is] easy to understand, the font and format appealing and the chapter layout clear and uncluttered...overall this is a useful pharmacokinetics book providing background information and guidance not only to academic students of Pharmacokinetics but also to those needing to apply the principles of pharmacokinetics to real-life clinical situations.'
Irish Pharmacy Journal, December 2006, 457

01-Oct-06, The Annals of Pharmacotherapy
'The editors have been successful in making Clinical Pharmcokinetics a quick reference for practical, real-life pharmacokinetic examples...this reference would be a useful supplemental guide for pharmacy students and a helpful addition to pharmacy libraries in patient-care arenas and colleges of pharmacy.'Laurie S Mauro, The Annals of Pharmacotherapy, 2006; 40: 1893

01-Oct-06, New Zealand Pharmacy
'This book is a very practical and relevant resource for any health professional working with drugs which require the application of pharmacokinetic principles because of their narrow therapeutic range, or with patients whose metabolism of drugs may be altered because of their age, renal or liver function...it would also be valuable for students wanting a current resource covering pharmacokinetic principles and relating them to clinical application.'
New Zealand Pharmacy, October 2006