Physicochemical Principles of Pharmacy

Physicochemical Principles of Pharmacy is an established textbook that provides you with full coverage of the physicochemical principles essential to the modern pharmacist and pharmaceutical scientist.

This sixth edition continues to boast a broad chemical and physicochemical base and covers every aspect of drug properties from the design of dosage forms to their delivery by all routes to sites of action in the body. Now with more clinical examples, new questions and extra case studies it encourages you to apply this knowledge and understand how these fundamental concepts relate to both clinical and industrial practice.

It features brand new chapters/sections on:

• Paediatric and geriatric formulations
• Adverse events: the role of formulations and delivery systems
• Generic medicines and biosimilars
• Solid dose form manufacture

Read our author interview.

Written by experienced academics and highly illustrated throughout, Physicochemical Principles of Pharmacy is an approachable and comprehensive resource that is perfect for supporting you through the physical pharmacy and drug delivery elements of pharmacy and pharmaceutical science courses.

1. Solids
2. Physicochemical properties of drugs in solution
3. Drug stability
4. The solubility of drugs
5. Surfactants
6. Emulsions, suspensions and related colloidal systems
7. Polymers and macromolecules
8. Drug absorption basics and the oral route
9. Parenteral routes of drug administration
10. Paediatric and geriatric formulations
11. Physicochemical interactions and incompatibilities
12. Adverse events: the role of formulations and delivery systems
13. Peptides, proteins and monoclonal antibodies
14. Pharmaceutical nanotechnology
15. Physical assessment of dosage forms
16. Generic medicines and biosimilars
    

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Australian Prescriber, October 2016

"The text is highly illustrated throughout and includes key points and appropriate examples, providing clinicians with some easily accessible and relevant information...

...Some examples of adverse events due to excipients, impurities, the influence of dosage forms, materials in delivery devices and even light-induced effects are also included. Although the detection of adverse events is not an easy task, these examples may assist clinicians in asking the right questions to predict or identify adverse effects...

...The new focus on applications to clinical practice in this edition has extended its usefulness from pharmacy and pharmaceutical scientist courses to clinicians seeking an understanding of formulations, especially for children and older people, and in identifying the cause of adverse events."

Beverley Glass, Australian Prescriber, October 2016.


The Pharmaceutical Journal, January 2016

"A standard text on physical pharmacy for students around the world.

...The sixth edition features new chapters or sections on paediatric and geriatric formulations, adverse events, generic medicines and biosimilars, and solid dose form manufacture...

...All chapters are well illustrated and tables are clearly set out. Key points and clinical points are highlighted and readers are able to work through calculations and refer to the answers which can be found close by...

...It fulfils an important requirement of describing the principles of physical pharmacy by using pharmaceutical examples to illustrate the topics."

Laurence A. Goldberg, The Pharmaceutical Journal, January 2016

Doody's Notes, March 2016

"Anyone interested in understanding the fundamental physicochemical principles and their application in formulation development should find this an excellent resource...

...This sixth edition has maintained its superior quality both in content and in presentation. It has been recognized as an excellent resource by pharmacy educators and students and by pharmaceutical scientists. I have been using this book for the last 10 years and I have found it to be invaluable."

Rahmat M. Talukder, PhD, RPh, Doody's Notes, March 2016.


From the reviews of previous editions:

"Changes in this edition include the new chapter on pharmaceutical nanotechnology, key learning points, more complete examples of clinical calculations, and a more clear distinction between the basic text and more complex theory. This recommended book is easy-to-read and is an asset to compounding and formulation pharmacists."

International Journal of Pharmaceutical Compounding, October 2011

"This book is excellent. It is the most accessible book I have read on the topic and is perfect for undergraduate pharmacy students."

Michael Taylor, Lecturer in Pharmaceutics, School of Pharmacy and Pharmaceutical Sciences, University of Central Lancashire, January 2010

"…an excellent reference for both graduate students and scientists in the pharmaceutical industry, as it provides and overview of the physicochemical principles important in pharmaceutics and biopharmaceutics."

Drug Development and Industrial Pharmacy, 33:209, 2007