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British National Formulary (BNF) 81

Published jointly by BMJ Publishing Group Ltd and Royal Pharmaceutical Society

The British National Formulary (BNF) is the first choice for concise medicines information. Trusted by healthcare professionals across the world to support confident decision-making at the point of care.

The new edition (BNF 81) provides up-to-date guidance on prescribing, dispensing, and administering medicines, plus legal and professional guidelines.

Extensive content updates in the BNF 81 edition include:

New monographs for:

  • Fetcroja ® [cefiderocol] for aerobic Gram-negative infections in patients with limited treatment options
  • Jyseleca ® [filgotinib] for rheumatoid arthritis
  • Myopridin® [pridinol] for central and peripheral muscle spasms
  • Nilemdo® [bempedoic acid] for primary hypercholesterolaemia or mixed dyslipidaemia in patients who have not responded adequately to other appropriate measures
  • Sunosi® [solriamfetol] for excessive sleepiness associated with narcolepsy
  • Veklury® [remdesivir] for COVID-19 in patients with pneumonia requiring supplemental oxygen
  • Zeposia® [ozanimod] for multiple sclerosis

New preparations:

  • Rybelsus ® [semaglutide]: oral formulation for type 2 diabetes
  • Spravato ® [esketamine]: intranasal spray for major depressive disorder

MHRA advice on:

  • Clozapine and other antipsychotics: monitoring blood concentrations for toxicity
  • Direct-acting oral anticoagulants (DOACs): reminder of bleeding risk, availability of reversal agents
  • Stimulant laxatives available over-the-counter: new measures to support their safe use
  • Cyproterone acetate: new advice and restrictions of use to minimise risk of meningioma
  • Insulins (all types): risk of cutaneous amyloidosis at injection site
  • Methotrexate once-weekly for autoimmune diseases: new measures to reduce risk of fatal overdose due to inadvertent daily instead of weekly dosing
  • Morphine and other opioids: new guidance to risk of dependence and addiction

Other significant changes include updated guidance on:

  • Influenza, Varicella-zoster and Haemophilus influenzae type b conjugate vaccine in-line with Public Health England recommendations
  • Management of venous thromboembolism
  • Management of uncomplicated gonorrhoea

BNF 81 is an essential publication, it provides you with:

  • Up-to-date information on prescribing, dispensing, and administering medicines
  • Authoritative, independent guidance on best practice enabling you to select safe and effective medicines
  • Information, you know you can trust for quality, reliability and independence
  • Everything you need at your fingertips, all in one book

BNF 81

New product




  • ISBN 9780857114105
  • Published Mar 2021
  • Paperback
    210x148x36mm (1824pp)

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